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ARTICLE
Year : 1993  |  Volume : 13  |  Issue : 1  |  Page : 185-188

Anti-inflammatory activiy of Premna tomentosa willd. in albino rats*


1 Captain Srinivasa Murti Drug Research Institute for Ayurvedic Arumbakkam, Madras - 600 106, India
2 Central Research Institute for Siddha**, Arumbakkam, Madras - 600 106, India

Correspondence Address:
Muzaffer Alam
Captain Srinivasa Murti Drug Research Institute for Ayurvedic Arumbakkam, Madras - 600 106
India
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Source of Support: None, Conflict of Interest: None


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An alcoholic extract of the leaves of Premna tomentosa  Willd at a dose of 100 mg/kg body weight exhibited significant anti-inflammatory activity in albino rats. The extract caused reduction in the weight of spleen, thymus and adrenals. It reduced cotton pellet granuloma by 32.21%. The serum biochemical parameters showed reduction in protein, acid phosphatase and transaminases. The activity of P. tomentosa was comparable to phenylbutazone.


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