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ARTICLE
Year : 2000  |  Volume : 20  |  Issue : 1  |  Page : 82-84

Antitumour activity of poochendurappattai in albino rats in albino rats


1 Assistant Director (Bio Chemistry) Bhubaneshwar, India
2 Laboratory Technician, CSMDRIA, Chennai, India
3 Research Assistant, CRI (S) Chennai, India
4 Assistant Research Officer, CSMDIA – Chennai, India
5 Assistant Director in-charge, CSMDIA – Chennai, India

Correspondence Address:
Muzaffer Alam
Assistant Director (Bio Chemistry) Bhubaneshwar
India
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Source of Support: None, Conflict of Interest: None


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The water extract of poochendurappattai was screened for antitumour activity at the doss of 5mg, 10mg, 20mg and 50 mg/kg body weight in rats against methylcholanthrene induced fibrosarcoma. There was 63% regression in the tumour weight at the doses of 10mg and 20 mg/kg body weight. This antitumour activity may be due to compounds like royaleanones since royaleanones are known to possess anticancer activity. Te phytochemical investigation of poochendurappattai revealed the presence of royaleanones.


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