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ARTICLE
Year : 2004  |  Volume : 23  |  Issue : 3  |  Page : 1-5

Bronchodilator effect of alcoholic extract of Euphorbia hirta Linn


Department of Pharmacology, Periyar College of Pharmaceutical Sciences, Sathanoor Main Road, Tiruchirappalli - 600 021, India

Correspondence Address:
S Karpagam Kumara Sundari
Department of Pharmacology, Periyar College of Pharmaceutical Sciences, Sathanoor Main Road, Tiruchirappalli - 600 021
India
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Source of Support: None, Conflict of Interest: None


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The bronchodilator effect of alcoholic extract of Euphorbia hirta Linn was evaluated at different doses (50,100 and 200mg/kg,p.o), using histamine aerosol test model. A dose dependent bronchodilator effect was observed in E. hirta pretreated animals. The extract of E. hirta at a dose of 200mg/kg was found to be more effective in histamine induced broncho constriction and a significant (p<0.001) effect was observed.


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