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ARTICLE
Year : 2004  |  Volume : 23  |  Issue : 4  |  Page : 23-29

Modulatory effects of lxora coccinea flower on cyclophosphamide toxicity in tumour bearing mice


Tropical Botanic Garden and Research Institute, Palode, Trivandrum - 695 562

Correspondence Address:
P G Latha
Tropical Botanic Garden and Research Institute, Palode, Trivandrum - 695 562

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Source of Support: None, Conflict of Interest: None


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The active fraction (AF) from lxora coccinea flowers prevented the decrease in haemoglobin levels and leucocyte counts of Dalton's lymphoma tumour bearing mice, treated with cyclophosphamide (CYP). It also significantly increased the life span of tumour bearing mice, treated with cyclophosphamide. Serum glutamate pyruvate transaminase (SGPT) and serum alkaline phosphatase (SAKP) levels of tumour bearing mice treated with CYP were decreased significantly by combination therapy with I.coccinea AF. indicating protection against hepatic toxicity.


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