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ARTICLE
Year : 2004  |  Volume : 24  |  Issue : 2  |  Page : 73-78

Hypocholesterolaemic effect of Spirulina and Liv-52 in lead induced toxicity in Albino rats


Department of Biochemistry, Dr. N.G.P.Arts & Science College, Coimbatore 641035, India

Correspondence Address:
K Jeyaprakash
Department of Biochemistry, Dr. N.G.P.Arts & Science College, Coimbatore 641035
India
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Source of Support: None, Conflict of Interest: None


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Effect of spirulina and Liv-52 on lead induced hypercholesteroleamia in albino rats was studied. Oral administration of lead acetate(10mg/kg body weight/day) for 30 days resulted in a significant increase(P<0.01) in the level of serum total cholesterol, triglycerides, LDL Cholesterol and a significant decreases in the level of serum HDL cholesterol, when compared to normal and control group of albino rats. Administration of either Liv-52 alone or in combination with spirulina produced a well pronounced protective effect against lead induced hypercholesteroleamia in rats. Although administration of spirulina alone caused an appreciable protective effect in lead toxicated tats, further study is needed with increased doses to evaluate its optimal effect.


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