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ARTICLE
Year : 2005  |  Volume : 25  |  Issue : 1  |  Page : 8-15

Effect of Terminalia arjuna stem bark extract on the activities of marker enzymes in alloxan induced diabetic rats


1 PSG College of Arts and Science, Coimbatore, Tamilnadu, India
2 Kongunadu Arts and Science College, Coimbatore, Tamilnadu, India

Correspondence Address:
B Ragavan
PSG College of Arts and Science, Coimbatore, Tamilnadu
India
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Source of Support: None, Conflict of Interest: None


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Insight of evidence that some complications of diabetes mellitus due to hyperglycemia, we investigated the effect of T.arjuna  bark extract on serum, liver and kidney marker enzymes in alloxan - induced diabetic rats. T. arjuna  was administered orally at a doses of 250 and 500 mg/kg body weight for 30 days, after which serum liver and kidney tissues were assayed for the degree of pathological changes by means of markers such as alkaline phosphatase (ALP), acid phosphatase (ACP), alanine amino transferase (ALT), aspartate amino transferase (AST) and lactate dehydrogenase (LDH) resulted in a significant reduction in serum and tissue of liver and kidney marker enzymes when compared with control rats T. arjuna  at a dose of 500 mg/kg body weight exhibited higher efficacy.


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