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ARTICLE
Year : 2010  |  Volume : 29  |  Issue : 3  |  Page : 19-21

Assessment of Anti-inflammatory activity of Taxus Baccata Linn. bark extract


1 Assistant Professor, Department of Pharmacy, IIMT College of Medical Sciences, 'O' Pocket, Ganga Nagar, Mawana Road, Meerut-250001, Uttar Pradesh, India
2 Department of Pharmaceutical Chemistry, Himalayan Pharmacy Institute, Majhitar, Rangpo, E.Sikkim-737136, Sikkim, India

Correspondence Address:
Satyajit Dutta
Assistant Professor, Department of Pharmacy, IIMT College of Medical Sciences, 'O' Pocket, Ganga Nagar, Mawana Road, Meerut-250001, Uttar Pradesh
India
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Source of Support: None, Conflict of Interest: None


PMID: 22557354

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Taxus baccata (L) known as Sthauneyaka in Sanskrit' has wide range of biological activities including analgesic, anti-malarial, anti-rheumatic, sedative, anti-spasmodic, aphrodisiac and anti-asthmatic. In the present study, the dried and powdered bark of Taxus baccata (L) was extracted with 95% ethanol and ether at room temperature and screened for their anti-­inflammatory activity by Carrageenan-induced paw edema method in rat. 95% ethanol extract exhibits potent anti-inflammatory activity at 200mg/kg four hours after administration in comparison with ether extract, as well reference standard, Aspirin. The observed pharmacological activities provide a scientific basis for the folklore use of the plant in treating acute inflammation.


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