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REVIEW ARTICLE
Year : 2017  |  Volume : 36  |  Issue : 4  |  Page : 175-181

Antidiabetic effects of artemisia species: A systematic review


1 Department of Biomedical, College of Health Sciences, Mizan Tepi University, Mizan Aman, Ethiopia
2 Department of Pharmacy, College of Health Sciences, Mizan Tepi University, Mizan Aman, Ethiopia

Correspondence Address:
Adane Teshome Kefale
Department of Pharmacy, College of Health Sciences, Mizan Tepi University, Mizan Aman
Ethiopia
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/asl.ASL_87_17

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Background: Over the last century, human life style and food habits have drastically changed which lead to various chronic diseases. Diabetes mellitus is one such disease which is causing serious problems to human health. Allopathic drugs are not much effective in handling the disease and its complications. Hence focus has been turned towards the traditional system of medicine. Medicinal plants play an important role in the management of diabetes mellitus. Methods: Experimental studies conducted on species of Artemisia on diabetic animal models and human published since the year 2000 until April, 2017 were reviewed. Each article was critically appraised by two independent reviewers for their methodological quality using the JBIMAStARI tool. Result: A total of 14 studies were included in this review and the blood glucose data obtained from these critically reviewed studies clearly showed that both the aqueous and alcoholic extracts of species of Artemisia produced significant hypoglycemic effects in alloxan, Streptozotocin and high fat diet induced diabetic animals and diabetic humans with different mechanisms of action as compared to standard antidiabetic medications. Discussion and Conclusion: The antidiabetic effect of single or multiple doses of aqueous and alcoholic extracts of Artemisia species was due to the active compounds of these plants and they all are effective in lessening the blood glucose level in all of those experimental studies. Despite the presence of known antidiabetic medicines in the pharmaceutical market, therapeutic remedies from these medicinal plants have been utilized with success to treat this disorder and its complications with a relatively less side effects.


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