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ARTICLE
Year : 1985  |  Volume : 4  |  Issue : 3  |  Page : 174-180

Ethanol induced metabolic alterations and the effect of phyllanthus niruri in their reversal


Department of Biochemistry, post-Graduate Institute of Basic Medical Sciences, University of Madras, Taramani, Madras - 600 113, India

Correspondence Address:
D Umarani
Department of Biochemistry, post-Graduate Institute of Basic Medical Sciences, University of Madras, Taramani, Madras - 600 113
India
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Source of Support: None, Conflict of Interest: None


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Phyllanthus niruri, Linn. (Kizha nelli in Tamil and Bahupatra and Bhumyamlaki in Sanskrit) which has been used widely for liver afflictions, was tried for its effectiveness in ethanol induced fatty liver, developed in rats, the increased deposition of triglyceride, cholesterol and phospholipid found in the liver, brain, kidney and heart due to ethanol administration were brought back towards the normal values on the administration of the herbal powder, however, in the intestine an d stomach the increased ATPase activity observed due to alcohol ingestion, was only partially reduced.


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