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ARTICLE
Year : 1993  |  Volume : 12  |  Issue : 3  |  Page : 451-461

Biochemical effects in normal and stone forming rats treated with the ripe kernel juice of plantain (Musa paradisiaca)


Department of Medical Biochemistry, P.G. Institute of Basic Medical Sciences, Taramani, Madras - 600 113, India

Correspondence Address:
V Kalpana Devi
Department of Medical Biochemistry, P.G. Institute of Basic Medical Sciences, Taramani, Madras - 600 113
India
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Source of Support: None, Conflict of Interest: None


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The effect of Musa paradisiaca stem kernel juice was investigated in experimental urolithiatic rats. Stone forming rats exhibited a significant elevation in the activities of two oxalate synthesizing enzymes - Glycollic acid oxidase and Lactate dehydrogenase. Deposition and excretion of stone forming constituents in kidney and urine were also increased in these rats. The enzyme activities and the level of crystalline components were lowered with the extract treatment. The extract also reduced the activities of urinary alkaline phosphatase, lactate dehydrogenase, r-glutamyl transferase, inorganic pyrophosphatase and β-glucuronidase in calculogenic rats. No appreciable changes were noticed with leucine amino peptidase activity in treated rats.


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