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ARTICLE
Year : 1998  |  Volume : 17  |  Issue : 4  |  Page : 290-299

Anti - tumour effect of Berberis asiatica Roxb. Ex. Dc. on dalton's lymphoma ascite


1 Department of pharmacology, J.S.S College of Pharmacy, Rocklands, Ootacamund 643 001, Tamil Nadu, India
2 Department of pharmacognosy, J.S.S College of Pharmacy, Rocklands, Ootacamund 643 001, Tamil Nadu, India

Correspondence Address:
E P Kumar
Department of pharmacology, J.S.S College of Pharmacy, Rocklands, Ootacamund 643 001, Tamil Nadu
India
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Source of Support: None, Conflict of Interest: None


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Berberis asiatica  Roxb. Ex. Dc., non Griff. Belongs to the family berberidaceae commonly occurring in the dry outer Himalaya, Assam etc. Roots along with stem bark s a reputed drug in Ayurvedic medicine contain several alkaloids. 50% Ethaolnic extract of roots reported to posses anti-cancer activity. The present study examines the antitumour effect of ethanolic root extract (BRE) against Dalton's lymphoma ascites tumour cells and solid tumour in swiss albino mice, A significant enhancement of mean survival time of BRE treated tumour bearing mice was found. Oral administration of BRE reduced the solid tumour induced by DLE and restored the altered haematological parameters to normal.


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