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ARTICLE
Year : 1999  |  Volume : 19  |  Issue : 1  |  Page : 25-27

Biochemical and hematological evaluations of Bryonia epigaea tubers


Department of Pharmaceutical Sciences, Birla Institute of Technology, Mesra, Ranchi 835 215, India

Correspondence Address:
B N Sinha
Department of Pharmaceutical Sciences, Birla Institute of Technology, Mesra, Ranchi 835 215
India
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Source of Support: None, Conflict of Interest: None


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Bryonia epigaea (cucurbitaceae) has been evaluated on various inflammatory models in rats in our laboratory. Ana anti-inflammatory drug(s) irrespective of its potency may not be devoid of undesirable effects on biochemical and hematological parameters. Alcoholic extract of Bryonia epigaaea (BE-Extract) at the dose of 50 mg/kg body weight, was administered to rats. Hepatotxic and nephrotoxic effects of BE-Extract were studies by measuring cholesterol, urea, uric acid, SGOT, SGPT and glucose levels in blood. Effects of BE-Extract on RBC count, WBC count, platelet count, hemoglobin content, clotting and bleeding time were also studied.


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