Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
Users Online: 1140 | Home Print this page Email this page Small font size Default font size Increase font size
ARTICLE
Year : 2007  |  Volume : 27  |  Issue : 1  |  Page : 50-55

Herbs containing L- Dopa: An update


Department of Pharmacognosy and Pharmacology, School of Pharmaceutical Sciences, Sri Padmavathi Mahila Visvavidyalayam, (Women's University) Tirupati, Andhra Pradesh, India

Correspondence Address:
B Ramya Kuber
Department of Pharmacognosy and Pharmacology, School of Pharmaceutical Sciences, Sri Padmavathi Mahila Visvavidyalayam, (Women's University) Tirupati, Andhra Pradesh
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


Rights and PermissionsRights and Permissions

L-Dopa is the drug of choice in the treatment of Parkinson's disease but it has dose related adverse effects such as nausea, vomiting, orthostatic hypotension, end of dose deterioration, on off phenomena and on chronic therapy motor complications synonymous to parkinsonism. Mucuna pruriens  (M.P) commonly known as velvet beans or cowitch are used in case of spasms associated with Parkins onism. Clinical efficacy of seeds of this plant was confirmed and the efficacy was contributed to its L-Dopa content. M.P extract showed twice the antiparkinsonism activity compared with synthetic L-Dopa. There is sufficient L-Dopa in broad bean (Vicia faba ) pods. One study proved its efficacy in Parkinsonism. Ginkgo biloba  extract showed protective effect in vivo and invitro. 50% ethanolic extract of Plumbago zeylanica  was effective in rats. The following plants were reported to have L-Dopa but their protective effect is yet to be established in animal models. Vigna aconitifolia, Vigna unguiculata, Vigna vexillata, Prosopis chilensis, Pileostigma malabarica, Phanera vahlis, Parkinsonia acculeata, Macuna urens, Canvavalia glandiata, Cassia floribanda, Casia hirsute and Dalbergia retusa  etc.


[PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed579    
    Printed39    
    Emailed0    
    PDF Downloaded74    
    Comments [Add]    

Recommend this journal