| ARTICLE |
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| Year : 2011 | Volume
: 31
| Issue : 1 | Page : 10-16 |
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Effect of ethanolic fruit extract of Cucumis trigonus Roxb. on antioxidants and lipid peroxidation in urolithiasis induced wistar albino rats
A Balakrishnan1, R Kokilavani1, K Gurusamy2, KS Ananta teepa3, M Sathya1
1 Department of Biochemistry, Kongunadu Arts and Science College, Coimbatore, India
2 Department of Biochemistry, Dr. N.G.P College of Arts and Science, Coimbatore, India
3 Department of Chemistry, V.P.M.M. Arts and Science College for Women, Krishnankoil, India
Correspondence Address:
A Balakrishnan
Department of Biochemistry, Kongunadu Arts and Science College, Coimbatore
India
 Source of Support: None, Conflict of Interest: None  | Check |
PMID: 22736884 
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Urolithiasis was induced using ethylene glycol in wistar albino rats, the formation of calcium stones in the kidney results with the damage of antioxidant system. Ethanolic extract of Cucumis trigonus Roxb fruit of family Curcurbitaceae was used to treat urolithiasis. On this course, the extract also repairs the changes that happened in the enzymatic, non enzymatic antioxidants and lipid peroxidation in liver and kidney of urolithiasis induced rats. The results obtained from the analysis were compared at 5% level of significance using one way ANOVA. The results show that the ethanolic fruit extract has repaired the levels of antioxidants and malondialdehyde to their normal levels. |
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