Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
Users Online: 551 | Home Print this page Email this page Small font size Default font size Increase font size
Year : 2013  |  Volume : 32  |  Issue : 6  |  Page : 22

OA02.16. Ayurvedic nanomaterials: Preparation and characterization of ginger loaded polymeric nanofibers for drug delivery applications

NanoBio Materials and Sensors Laboratory, PSG Institute of Advanced Studies

Correspondence Address:
D Ravi Shankaran
NanoBio Materials and Sensors Laboratory, PSG Institute of Advanced Studies

Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0257-7941.123836

Rights and Permissions

Purpose: The purpose of this study is to combine nanotechnology and ayurveda to develop novel ayurvedic nano materials with enhanced functionalities towards betterment of the clinical practices. In this context, we have fabricated ginger loaded polymeric nano fibers. Ginger is an important ayurvedic material because it exhibits a wide range of biological and pharmacological activities including antioxidant, antiinflammatory, antibacterial, antifungal, antiparasitic, anticancer and detoxifying properties. Incorporation of ginger with polymeric materials enables high-performance drug delivery systems. Method: Nano fibers are produced by electro spinning method using poly(methyl methacrylate) (PMMA) and gelatin polymers. Electro spinning is a simple and versatile method for fabrication of nano fibers with high surface to volume ratio. The electro spinning parameters are optimized with respect to flow rate, voltage between the two electrodes, tip collector distance to obtain fine nano fibers without beads. After optimization, ginger loaded nano fibers are fabricated by mixing ginger with polymer before electro spinning. Result: The fibers were characterized by various techniques such as optical microscope, Fourier transform infrared spectroscope (FTIR), UVVis spectroscope, atomic force microscope (AFM) and high resolution transmission electron microscope (HRTEM). The studies showed uniform and smooth fibers (hollow fibers) loaded with ginger. The average diameter of the nano fibers is in the range of 100 to 600 nm. The UVVis studies showed the release of the drugs with respect to time depending on the morphology of the fiber and medium. Conclusion: Ginger loaded nano fibers are successfully fabricated with smooth surface without beads. The ginger release studies demonstrated a slow release of ginger from the nano fibers. The results demonstrate that the ginger loaded nano fiber could be a good candidate to manage various diseases, specifically, rheumatic diseases, joint pains and migraine. This work provides an opportunity to expand the medical benefits of combined nanotechnology and ayurveda.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded57    
    Comments [Add]    

Recommend this journal