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Year : 2016  |  Volume : 35  |  Issue : 3  |  Page : 185

Black pepper: Stimulation of diarrhea in patient with underlying short bowel syndrome


1 Vitallife Wellness Center, Bumrungrad International Hospital, Bangkhae, Bangkok, Thailand
2 Wiwanitkit House, Bangkhae, Bangkok, Thailand

Date of Web Publication8-Apr-2016

Correspondence Address:
Kamon Chaiyasit
Vitallife Wellness Center, Bumrungrad International Hospital, Bangkok
Thailand
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0257-7941.179872

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How to cite this article:
Chaiyasit K, Wiwanitkit V. Black pepper: Stimulation of diarrhea in patient with underlying short bowel syndrome. Ancient Sci Life 2016;35:185

How to cite this URL:
Chaiyasit K, Wiwanitkit V. Black pepper: Stimulation of diarrhea in patient with underlying short bowel syndrome. Ancient Sci Life [serial online] 2016 [cited 2020 Oct 30];35:185. Available from: https://www.ancientscienceoflife.org/text.asp?2016/35/3/185/179872

Sir,

Black pepper is a well-known plant which has been widely used as regimen in ancient drug remedies. The antibacterial activity of the berries of black pepper is confirmed.[1] As an important drug in Indian Ayurveda remedies, black pepper's usefulness is also confirmed in the management of hyperglycemia and metabolic disruption.[2],[3] Focusing on the gastrointestinal effect, there is a new evidence that piperine from black pepper can act against diarrhea.[4] However, we hereby present an observation against this recent finding. The patient is a case with underlying short bowel syndrome with controllable bowel frequency. The patient had just tried adding black pepper as an ingredient to her food and got the acute problem of diarrhea for more than 10 times per day. The stool examination and culture was done and the result was negative. After ceasing of using black pepper, there was complete relief from diarrhea. She performed a self-provocative test by adding black pepper into her food again and the diarrhea problem resurfaced. She also observed that more pepper resulted in greater frequency of diarrhea. The above case gives an interesting data against the observation that black pepper might be useful for control of diarrhea. It is also noted that the patient with underlying bowel disorder (such as short bowel syndrome or irritable bowel syndrome) should be aware of any Ayurveda regimen that may contain black pepper.

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  References Top

1.
Reddy SV, Srinivas PV, Praveen B, Kishore KH, Raju BC, Murthy US, et al. Antibacterial constituents from the berries of Piper nigrum. Phytomedicine 2004;11:697-700.  Back to cited text no. 1
    
2.
Sudha P, Zinjarde SS, Bhargava SY, Kumar AR. Potent a-amylase inhibitory activity of Indian Ayurvedic medicinal plants. BMC Complement Altern Med 2011;11:5.  Back to cited text no. 2
    
3.
Mutheeswaran S, Pandikumar P, Chellappandian M, Ignacimuthu S. Documentation and quantitative analysis of the local knowledge on medicinal plants among traditional Siddha healers in Virudhunagar district of Tamil Nadu, India. J Ethnopharmacol 2011;137:523-33.  Back to cited text no. 3
    
4.
Pongkorpsakol P, Wongkrasant P, Kumpun S, Chatsudthipong V, Muanprasat C. Inhibition of intestinal chloride secretion by piperine as a cellular basis for the anti-secretory effect of black peppers. Pharmacol Res 2015;100:271-80.  Back to cited text no. 4
    



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