Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
Users Online: 140 | Home Print this page Email this page Small font size Default font size Increase font size
ORIGINAL ARTICLE
Year : 2016  |  Volume : 35  |  Issue : 4  |  Page : 207-211

Hypoglycemic and anti-hyperglycemic activity of Triphalādi granules in mice


1 Department of Kayachikitsa, IPGT and RA, Gujarat Ayurved University, Jamnagar, Gujarat, India
2 Department of Rasashastra and Bhaishajya Kalpana, IPGT and RA, Gujarat Ayurved University, Jamnagar, Gujarat, India
3 Department of Pharmacology, Pharmacology Laboratory, IPGT and RA, Gujarat Ayurved University, Jamnagar, Gujarat, India

Correspondence Address:
Ankush Gunjal
Department of Kayachikitsa, IPGT and RA, Gujarat Ayurved University, Jamnagar - 361 008, Gujarat
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0257-7941.188177

Rights and Permissions

Background: Triphalādi kvātha is well known herbal Ayurvedic formulation used in Prameha (~type 2 diabetes mellitus). In the present study, kvātha was converted into granules and assessed for its hypoglycemic and anti-hyperglycemic effects in albino mice. Materials and Methods: Triphalādi granules (650 mg/kg, p.o.) were administered in normal albino mice for assessment of hypoglycemic activity. Anti-hyperglycemic activity of Triphalādi granules was assessed in glucose (5 g/kg, p.o.) solution overloaded mice. The blood sugar level (BSL) was measured with the help of one touch easy glucometer. Results: Triphalādi granules produced significant decrease in blood glucose level after one hour in comparison to initial values while decreasing BSL by 27.92% in comparison to control group in normal albino mice. In hyperglycemic study, Triphalādi granules produced significant decrease the BSL after 2 hr. of administration compared to control group. Conclusion: Triphalādi granules have significant hypoglycemic and anti-hyperglycemic activity in mice with minimal effect on BSL below normal range. The studies suggest the potential role of Triphalādi granules as an alternative adjuvant therapy in diabetic individuals for the control of the blood glucose level.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed2815    
    Printed41    
    Emailed0    
    PDF Downloaded108    
    Comments [Add]    
    Cited by others 1    

Recommend this journal