Year : 2013 | Volume : 32 | Issue : 6 | Page : 29-
OA03.06. A clinical study to evaluate the efficacy of amritadya guggulu on elevated lipid profile.
U Ajay Bhat
Alvas Ayurveda Medical College, Karnataka, India
Purpose: Hyperlipidaemia has gained world wide interest in its ability to participate in the pathology of atherosclerotic diseases like coronary heart disease (CHD) which dominates the scenario of diseases causing morbidity and mortality in the world. Hyperlipidaemia is a term used to denote raised serum levels of cholesterol or triglycerides or both. Raised cholesterol is estimated to cause 18% of the global cerebrovascular disease and 56% of global ischemic heart disease. Overall this amounts to about 4.4 million deaths (7.9% of total) annually. Raised total cholesterol is a major cause of disease burden in both the developed and developing world as a risk factor for ischemic heart disease and stroke. Every 1% decrease in cholesterol decreases CHD risk by 2.5%. Method: Randomized single group, single intervention observational study of sample size: 30. Assessment was done based on lipid profile values pre and post treatment. One tab «DQ»Amritadya Guggulu«DQ», 475mg TID with water, after food, for a period 30 days. Follow up was taken on 31st day. Result: After treatment S.Cholesterol showed an average of 21.96% decrease, On S.LDL at an average of 30.47% decrease, On S.VLDL average of 20.77% decrease, S. TRIGLYCERIDES average of 26.32% decrease at p<0.001 respectively. S.HDL showed an average of 1.40% increase at p>0.5. 60% of patients had an average increase in S.HDL by 9.27% and 28.30% decrease in other parameters, however 40% of patients had an average decrease of 8.62% and 23.01% decrease in other parameters in S.HDL. Conclusion: Amritadya guggulu has given significant result on elevated lipid profile, even though it has decreased S.HDL in minority patients, the change may be corrected, subject to lifestyle changes.