Year : 2013 | Volume : 32 | Issue : 6 | Page : 40-
OA03.17. Pilot retrospective observational study to evaluate efficacy of customized ayurvedic therapy on Type 2 diabetes exhibiting secondary failure of oral hypoglycemic drugs
The Arya Vaidhya Chikitshalayam and Research Institute, Coimbatore, India
Purpose: The data was retrospectively collected through third part unbiased documentation conducted under RUDRA program at The Arya Vaidhya Chikitsalayam and Research Institute. Obtained data was evaluated to study the efficacy of customized ayurvedic therapy in on Type 2 diabetes exhibiting secondary failure of oral hypoglycemic drugs. Method: Participants were retrospectively selected between Jan. to Dec. 2011 diagnosed with Type 2 Diabetes mellitus as primary or secondary morbidity during documentation. Out of 194 patients who visited our OPD with primary aim as management of their type 2 diabetes 27 cases found to have adequate baseline and endpoint data and satisfying the inclusion criterion were delineated, exhibiting secondary failure to oral hypoglycemic drug . At least 1 prescription claim for a sulfonylurea or a thiazolidinedione during study period along with metformin use include in the study. Secondary failure was measured for patients who initially achieved a Fasting and Post prandial blood glucose 126 mg/dl and 200 mg/dl but in due course of chronicity again rose above the said level, exhibiting secondary failure of oral hypoglycemic drugs Result: Participants (mean age, 50.034 (S.D. μ13.64) years; 55.6% female and 44.4 % males) who were known diabetic since 5.9185 (S.D. μ6.6) underwent a customized Ayurveda treatment with Allopathic oral hypoglycemic drugs as concomitant medication for average of 16.2 weeks. The mean baseline Fasting and Post prandial blood glucose was 163.26 (S.D. μ50.57) and 230.23 (S.D.μ 90.24244) and which was higher for the patients receiving a combination of metformin and sulfonylurea or thiazolidinedione. The mean Fasting blood glucose decreased to 131.49, and Post prandial 174.5 of patients as compared to baseline. This reduction in the Gycemic index was found to be statistically significant after administration of unpaired students «SQ»t«SQ» test at significance level of <0.05. Conclusion: Customized Ayurveda treatment was able to ameliorate the Fasting and Post prandial blood sugar levels in patients with secondary failure to oral hypoglycemic drugs with type 2 diabetes.