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REVIEW ARTICLES
Tinospora cordifolia
: One plant, many roles
Soham Saha, Shyamasree Ghosh
April-June 2012, 31(4):151-159
DOI
:10.4103/0257-7941.107344
PMID
:23661861
Natural products with medicinal value are gradually gaining importance in clinical research due to their well-known property of no side effects as compared to drugs.
Tinospora
cordifolia
commonly named as "Guduchi" is known for its immense application in the treatment of various diseases in the traditional ayurvedic literature. Recently the discovery of active components from the plant and their biological function in disease control has led to active interest in the plant across the globe. Our present study in this review encompasses (i) the genetic diversity of the plant and (ii) active components isolated from the plant and their biological role in disease targeting. The future scope of the review remains in exploiting the biochemical and signaling pathways affected by the compounds isolated from
Tinospora
so as to enable new and effective formulation in disease eradication.
[ABSTRACT]
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14,729
1,915
51
ORIGINAL ARTICLE
Evaluation of Ratnaprash for its effect on strength, stamina and fatigue using swim endurance test and biochemical estimation in swiss albino mice
Arun Gupta, Satyendra Kumar, Rashmi Rajput, Ruchi Srivastava, Rajiv K Rai, J. L. N. Sastry
July-September 2015, 35(1):26-31
DOI
:10.4103/0257-7941.165626
PMID
:26600664
Context:
Traditional medicines have been considered as important resources for postponing fatigue, accelerating elimination of fatigue related metabolites and improving physical ability.
Rasāyanās
or rejuvenative therapies are mentioned as one of the eight clinical specialties in Ayurveda for attaining longevity, healthy life and regulation of bodily balance. Eventhough more detailed studies are needed to confirm the claims of benefits in the light of evidence based research, Ratnaprash, a herbo-mineral
rasāyana
formulation, is proposed here to be an antifatigue supplement that is good in promoting strength and stamina.
Materials and Methods:
In the present study, anti fatigue, strength and stamina enhancing properties of Ratnaprash were examined based on swim endurance capacity and the change in biochemical parameters in Swiss Albino mice. Treatment groups were orally administered Ratnaprash at various test doses (500, 1000, 2000 mg/Kg per day), while the control group received distilled water at similar dose volumes. Effect of therapy was evaluated after 28 days of treatment.
Results:
At the end of study period, the swimming times to exhaustion were longer in the treated groups than in the control group. Plasma lactate levels of treated groups were lower than those of the control group (
P
< 0.05) while tissue ATP levels were higher. These effects were dose dependent and the strongest effect was seen in groups treated at 1000 mg/Kg.
Conclusion:
Ratnaprash enhanced the forced swimming capacity of mice and exhibited elevated anti-fatigue activity, reduced blood lactate levels and increased tissue ATP levels in preclinical models in comparison to vehicle control, exhibiting possible role in increasing strength and stamina and contributing anti-fatigue activity.
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1
REVIEW ARTICLES
Identity of
Ṭaṅkārī
(
Physalis Minima
Linn.) in Ayurvedic Classics: A Literature Review
Supriya S Kallianpur, Rohit A Gokarn, N Rajashekhar
July-September 2016, 36(1):6-11
DOI
:10.4103/0257-7941.195408
PMID
:28182025
Proper identification of drugs and their use in proper doses are important for successful treatment.
Physalis minima
Linn commonly known as country gooseberry has anti-cancerous, anti-diabetic, analgesic, antipyretic and anti-inflammatory potentials. The present paper is aimed to ascertain the proper identity of
Ṭaṅkārī
(
Physalis minima
Linn.) in Ayurvedic classics by a meticulous search and hence a review of the drug
Ṭaṅkārī
(
Physalis minima
Linn) was carried out in the texts of Ayurveda, modern literature, journals and online publications. The result of the search showed that the name “
Ṭaṅkārī
” is not found in Vedic lore. In Saṃhitās, it is mentioned in Bhāvaprakāśa. Reference of the drug “
Śārṅgeṣṭhā
” is found in Bṛhattrayī, Bhela, Kāśyapa, Cakradatta and Vaṅgasena. It is variously named as
Cirapoṭikā
,
Kākatikta
, and
Vāyasī
by ḍalhaṇa and he describes it as gaura (pale), vartula (round), and as having
avaguṇṭhita
/
veṣṭhita
(covered) fruit which matches the description of
Ṭaṅkārī
(
P. minima
Linn). A search for terms
Kākatikta
and
Vāyasī
showed
Kākatikta
to be synonymous to
Śārṅgeṣṭhā
and
Vāyasī
to be synonymous to both
Kākatikta
and
Kākamācī
(
Solanum nigrum
). Madanapāla and Śāligrāma Nighaṇṭus have mentioned the name
Cirapoṭikā
to be synonymous with
Ṭaṅkārī
. Śodhala has used the term Parpoṭī as a synonym of
Ṭaṅkārī
, which is the Gujarati name of
P. minima
Linn. Recent authors have considered
Śārṅgeṣṭhā
as either
P. minima
or
Cardiospermum helicabum
. The regional names of
P. minima
are
Cirpoṭi
(Hindi),
Cirboli
(Marathi), also the folklore uses and pharmacological activities of
P. minima
are in accordance with the indications of
Śārṅgeṣṭhā
in classics. Thus with a complete review of both Ayurveda and modern literatures, it can be concluded that the drug mentioned as
Ṭaṅkārī
in Bhāvaprakāśa is the same as
Śārṅgeṣṭhā
mentioned in the classics.
Cirapoṭikā
and
Kākatikta
are its synonyms.
Cardiospermum helicabum
is
Karṇaspoṭha
, and hence
Śārṅgeṣṭhā
of classics is
P. minima
which is supported by the regional names, pharmacological activity and folklore claims.
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ARTICLES
Ancient concept of metal pharmacology based on Ayurvedic literature
Prasanta Kumar Sarkar, Sanjita Das, PK Prajapati
April-June 2010, 29(4):1-6
PMID
:22557360
Metals have had a long history in Ayurvedic system of medicine. Mercury (Parada), gold (Swarna), silver (Rajata), copper (Tamra), iron (Lauha), tin (Vanga), lead (Naga), and zinc (Yasada) are used in therapeutics in an incinerated (Bhasma) form. The pharmacological actions, therapeutic indications, adverse effects and management of adverse effects of these metals are described and emphasis has been given to the proper preparation, rational dose and duration during clinical practice in the classics of Ayurveda. Most important observation is, there are no contraindications of these Bhasmas, indicating universal applicability to all age levels with suitable adjuvant, proper dose and duration.
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Medico - botanical study of Yercaud hills in the eastern Ghats of Tamil Nadu, India
M Parthipan, V Aravindhan, A Rajendran
April-June 2011, 30(4):104-109
The study reports medicinal plant survey was conceded in Yercaud hills ranges of Eastern Ghats, Tamil Nadu, India. The study primarily based on field surveys conducted throughout the hills, where dwellers provided information on plant species used as medicine, plant parts used to prepare the remedies and ailments to which the remedies were prescribed. The study resulted about 48- plant species belonging to 45- genera and 29- families of medicinal plants related to folk medicine used by the local people. Among them the most common plants viz., Asparagus racemosus Willd., Cissus quadrangularis L., Gymnema sylvestre R. Br., Hemidesmus indicus (L.) R. Br., Justisia adhatoda L., Ocimum sanctum L., Phyllanthes amarus Schum. & Thonn., Piper nigrum L., Solanum nigrum L., Tinospora cordifolia (Thunb.) Miers, Tridax procumbens L. and Zingiber officinale Roscoe which are used in their daily life to cure various ailments.
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ORIGINAL ARTICLES
Experimental evaluation of
Hiṅgvādi Ghṛta
in behavioral despair using animal models
Poonam Ashish Gupte, Jayshree Dawane, Asmita Ashish Wele
October-December 2016, 36(2):84-89
DOI
:10.4103/asl.ASL_78_16
PMID
:28446829
Context:
Depression, a sustained mood disorder caused by selective diminution of specialized cells in brain is increasing at an alarming rate. It will be the second largest morbid illness by next decade and is the leading cause of suicidal deaths. The available antidepressant medications benefit only a third of its recipients and have many side effects. Hence, it is imperative to search in Ayurveda for leads.
Aim:
To evaluate Anti- depressant activity of
Hiṅgvādi Ghṛta in vivo
.
Settings and Design:
Comparative preclinical study.
Materials and Methods:
Hiṅgvādi Ghṛta
(HG) was prepared using standard operating procedure, physicochemically analyzed and assessed. Tail Suspension Test (TST) model with Swiss albino mice and Forced Swim Test (FST) model with Wistar albino rats were used to assess anti-depressant activity. Imipramine hydrochloride in dose of 15 mg/kg for TST and 10 mg/kg for FST, was the standard drug and
Ghee
as vehicle control in dose of 0.1g/20g for TST and 0.72g/200g for FST orally.
Hiṅgvādi Ghṛta
in doses of 0.05g/20g (x/2), 0.1g/20g (x) and 0.2 g/20g (2x) for TST and 0.36g/200g (x/2), 0.72g/200g (x) and 1.44g/200g (2x) for FST was administered to 3 test groups for 21 days orally except Plain control group which received only distilled water. Duration of immobility in seconds for TST and number of rotations for FST were noted for assessment.
Statistical Analysis Used:
One way ANOVA followed by Dunnets test and Paired
t
test.
Results:
HG was significantly effective at dose of 0.1gm/20gm for TST (
P
= 0.0037;
P
< 0.01) and 0.72g/200g for FST (
P
= 0.0055,
P
< 0.01) comparable to Imipramine hydrochloride.
Conclusions:
HG displayed potent anti depressant activity comparable to standard drug Imipramine Hydrochloride.
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65
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REVIEW ARTICLE
A review on phyto‑pharmacological potentials of
Euphorbia thymifolia
L.
Prashant Y Mali, Shital S Panchal
January-March 2013, 32(3):165-172
DOI
:10.4103/0257-7941.123001
PMID
:24501446
Euphorbia
thymifolia
L. (
Euphorbiaceae
) is a small branched, hispidly pubescent, prostate annual herb, commonly known as
laghududhika
or
choti
-
dudhi
. The leaves, seeds and fresh juice of whole plant are used in worm infections, as stimulant, astringent. It is also used in bowel complaints and in many more diseases therapeutically. The present work is an extensive review of published literature concerning phytochemical and pharmacological potential of
E.
thymifolia
. Data was searched and designed using various review modalities manually and using electronic search engines with reference to all aspects of
E.
thymifolia
and was arranged chronologically. Complete information of the plant has been collected from the various books and journals since the last 32 years, internet databases, etc., were searched. Compiled data reflects the safety and therapeutic efficacy of the plant. This will be helpful for researchers to focus on the priority areas of research yet to be explored and in scientific use of the plant for its wide variety of traditional therapeutic claims and also as to find out new chemical entities responsible for its claimed traditional activities.
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9,009
405
7
ORIGINAL ARTICLES
Estimation of total alkaloid in
Chitrakadivati
by UV-Spectrophotometer
Manjunath Ajanal, Mahadev B Gundkalle, Shradda U Nayak
April-June 2012, 31(4):198-201
DOI
:10.4103/0257-7941.107361
PMID
:23661869
Background:
Herbal formulation standardization by adopting newer technique is need of the hour in the field of Ayurvedic pharmaceutical industry. As very few reports exist. These kind of studies would certainly widen the herbal research area. Chitrakadivati is one such popular herbal formulation used in Ayurveda. Many of its ingredients are known for presence of alkaloids.
Methodology:
Presence of alkaloid was tested qualitatively by Dragondroff's method then subjected to quantitative estimation by UV-Spectrophotometer. This method is based on the reaction between alkaloid and bromocresol green (BCG).
Results and Conclusion:
Study discloses that out of 16 ingredients, 9 contain alkaloid. Chitrakadivati has shown 0.16% of concentration of alkaloid and which is significantly higher than it's individual ingredients.
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16
BOOK REVIEW
The 'Pāka
darpaṇam
': The text on Indian cookery by King Nala
Naveen Kodlady
April-June 2014, 33(4):259-262
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7,375
466
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ARTICLES
Biopotency of
Acalypha indica
Linn on Membrane Bound ATPases and Marker Enzymes urolithic Rats
M Sathya, R Kokilavani, KS Ananta Teepa, A Balakrishnan
July-September 2011, 31(1):3-9
PMID
:22736883
The ethanolic extract of
Acalypha indica
was tested for its biopotency on membrane bound enzymes and marker enzymes in urolithiasis in male wistar albino rats. Calcium oxalate urolithiasis was induced by 0.75% ethylene glycol in drinking water for 30 days. There was a significant decrease in membrane bound enzymes such as Ca
2+
ATPase, Mg
2+
ATPase, Na
+
K
+
ATPase and marker enzymes Aspartate Transaminase (AST), Alanine Transaminase (ALT), Acid phosphatase (ACP) and Alkaline Phosphatase (ALP) in liver and kidney. The AST, ALT, ACP and ALP were increased in serum and urine of rats. Therapeutic treatment with plant extract (200mg/kg b.wt.dose
-1
day
-1
oral
-1
) has significantly ameliorated to near normalcy in the curative group. These results of the present study concluded that A. indica can play an important role in the prevention of disorders associated with kidney stone formation .
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Nomenclature of
Anukta Dravya
Ganji Kusuma, VK Joshi
April-June 2010, 29(4):17-23
PMID
:22557363
Field survey was conducted in rural areas of Varanasi district of Uttar Pradesh including Ramnagar, Manduadih and surrounding areas to identify and collect information on undocumented medicinal plants (Anukta Dravya) by direct interaction with folklore people through field survey and indirect means by means of comprehensive survey of available literature. Local names of undocumented medicinal plants along with other relevant information were collected, after recording local names of medicinal plants, their botanical identification was done by comprehensive survey of literature, and the plants were identified according to Bentham & Hooker's system of classification using local floristic works. Expert opinion of plant taxonomists was also sought for cross checking and confirmation on identity. The freshly collected specimens were photographed for visual identification of the species. After identification, nomenclature of 10 Anukta Dravya was done as per the criteria of nomenclature mentioned in Nighantus.
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SHORT COMMUNICATIONS
Antiulcer activity of Amlapitta Mishran suspension in rats: A pilot study
Sampath K Vemula, Mukesh B Chawada, Kapil S Thakur, Mahesh K Vahalia
October-December 2012, 32(2):112-115
DOI
:10.4103/0257-7941.118551
PMID
:24167338
Context:
Amlapitta Mishran suspension is a poly herbal ayurvedic formulation, which has been traditionally used for acidity and gastric ulcers.
Aim:
The aim of this study is to evaluate the antiulcer activity of Amlapitta Mishran on non-steroidal anti-inflammatory drugs (NSAID's) -induced ulcers in the rat model.
Subjects and Methods:
The antiulcer activity of Amlapitta Mishran was investigated on indomethacin (100 mg/kg) NSAID's induced ulcers in rats. Effect of two different doses of Amlapitta Mishran was studied by calculating the total number of ulcers, ulcer index and percentage inhibition.
Statistical Analysis Used:
Data was analyzed by the Student's
t-
test (
P
< 0.05).
Results:
Amlapitta Mishran treated rats have shown significant (
P
< 0.0001) decrease in the total number of ulcers and ulcer index and significant increase in % inhibition of ulcers as compared with positive control group.
Conclusion:
The results indicate that Amlapitta Mishran has showed a dose dependent antiulcer activity in experimental animals and confirms ayurvedic use of Amlapitta Mishran in gastric ulcers.
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6,898
172
2
CASE REPORTS
An approach to avascular necrosis by
Saghṛta kṣīrabasti
Sreelaksmi Chaganti, Rajashekhar V Sanipeti, Suma S. S Joshi
July-September 2013, 33(1):45-48
DOI
:10.4103/0257-7941.134602
PMID
:25161330
A 62-year-old, male patient radiologically diagnosed as a case of avascular necrosis of femur head with grade 4, presented the following chief complaints. Pain in the left hip joint radiating to thigh (anterior part), of grade '9' on “visual analog scale (VAS)” associated with swelling in bilateral feet and decreased range of movements in the hip joint. This presentation was correlated with
Asthi-majjagata v
ā
ta (musculo-skeletal disorder)
and treated accordingly. Initially, patient had been administered
d
ī
pana
and
p
ā
cana
followed by
nityavirecana
(therapeutic purgation). Further
Saghrita k
ṣ
ī
rabasti
(medicated enema prepared with milk and ghee) was administered in
kal
ā
basti
schedule (16 in number). This resulted with relief of pain to grade “3” on “VAS” and complete resolution of pedal edema and improvement in range of movement of hip joint.
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249
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ORIGINAL ARTICLES
Quality control parameters for
Tamra
(copper)
Bhasma
Chandrashekhar Yuvaraj Jagtap, Pradeepkumar Prajapati, Biswajyoti Patgiri, Vinay J Shukla
April-June 2012, 31(4):164-170
DOI
:10.4103/0257-7941.107348
PMID
:23661863
Background:
Metallic
Bhasmas
are highly valued and have their own importance in Ayurvedic formulations. To testify the
Bhasmas
various parameters have been told in
Rasashastra
classics.
Tamra Bhasma
(TB) with its different properties is used in the treatment of various diseases is quiet famous among the Ayurvedic physicians (
Vaidyas
).
Objectives:
The present study was carried out to set up the quality control parameters for the TB by making the use of classical tests along with advanced analytical tools.
Settings and Design:
Copper wire taken for the preparation of
Bhasma
was first analyzed for its copper content and then subjected to
Shodhana, Marana
and
Amrutikarana
procedures as per the classical references. Final product complied with all the classical parameters like
Rekhapurnatwa
, Varitaratwa etc.
Materials and Methods:
After complying with these tests TB was analyzed by advanced analytical techniques like particle size distribution (PSD) analysis, scanning electron microscopy (SEM), and inductive coupled plasma spectrometry (ICP).
Results:
PSD analysis of TB showed volumetric mean diameter of 28.70 μm, 50% of the material was below 18.40 μm size. Particle size less than 2μm were seen in SEM. 56.24 wt % of copper and 23.06 wt % of sulphur was found in ICP-AES. Heavy metals like cadmium, selenium were not detected while others like arsenic, lead and mercury were present in traces.
Conclusions:
These observations could be specified as the quality control parameters conforming to all the classical tests under the
Bhasma Pariksha
.
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5,992
580
1
ARTICLES
Physico-Phytochemical investigation and anti-inflammatory screening of capsicum annum L. and Hemidesmus indicus (Linn.) R. Br.
K Vijayalakshmi, R Shyamala, V Thirumurugan, M Sethuraman, S Rajan, Shrishailappa Badami, Pulok K Mukherjee
April-June 2010, 29(4):35-40
PMID
:22557366
Capsicum annum L. (Family: Solanaceae) and Hemidesmus indicus (Linn.) R.Br. (Family: Asclepiadaceae) are commonly used in Tamilnadufor treating various ailments in the native system of medicine. The hydroalcoholic extracts of both plants at dose level of 100 mg/kg body weight showed demonstrable anti-inflammatory activity in the carrageenan-induced hind paw model in rats. Nevertheless, the overall anti-inflammatory activity exhibited by the extracts are found to be less as compared with that of standard drug Indometacin. Preliminary physico-phytochemical analysis of the plants in question were attempted. The results are highlighted and discussed.
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Leech Therapy- A Holistic Approach of Treatment in Unani (Greeko-Arab) Medicine
Azad Hussain Lone, Tanzeel Ahmad, Mohd Anwar , Shahida Habib, Gh Sofi , Hashmat Imam
July-September 2011, 31(1):31-36
PMID
:22736888
The Unani System of Medicine also known as Greeko-Arab medicine, founded by Hippocrates is based on the concept of equilibrium and balance of natural body humours (blood, bile, black bile and phlegm). The imbalance in the quality and quantity of these humours leads to diseases whereas restoration of this balance maintains health of a person. The treatment methodology of diseases is based on four therapeutic modalities viz. Regimental therapy, Dieto-therapy, Pharmacotherapy and surgery. Irsale Alaq (Leech or Hirudo therapy) is one of the most important and widely practised methods of regimental therapy used for local evacuation of morbid humours. It is a procedure of treatment with the use of medicinal leeches. It has been suggested and successfully practised by Greeko-Arab physicians in the management of musculoskeletal diseases, gynaecological disorders, chronic skin diseases, thromboembolic diseases, varicose veins, ENT disorders etc since long. According to Unani doctrine, the efficacy of leech therapy is attributed to the analgesic and resolvent activities of leeches. However, from modern perspective, the saliva of leech contains about 100 pharmacologically active biological substances like Hirudin, hyaluronidase, vasodilators, anesthetics, antibacterial, fibrinases, collagenase etc. These substances are injected into human body while sucking of the blood and are responsible for the analgesic, anti inflammatory and anesthetic effects of leech therapy.
[ABSTRACT]
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5,998
406
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ORIGINAL ARTICLES
Physico-chemical standardization of
Sitopaladi churna
Inder Kumar Makhija, Chandrashekara Shastry Shreedhara, Holavana Hally Nanjundaiah Setty Aswatha Ram
January-March 2012, 31(3):107-116
DOI
:10.4103/0257-7941.103187
PMID
:23284216
Background:
Standardization of a compound Ayurvedic formulation is a critical and essential issue to be considered in assuring the therapeutic efficacy and safety and to rationalize their use in the health care.
Sitopaladi churna
is a reputed polyherbal formulation of Ayurveda. It is prescribed for the treatment of pleurodynia, intercostal neuralgia, cold, cough associated with bronchitis, pneumonia, tuberculosis, viral respiratory infection, and in pharyngeal and chest congestion.
Objective:
The present study aimed at physico-chemical standardization of in-house and two marketed brands of
Sitopaladi churna
.
Materials and Methods:
In our investigation, in-house churna and two commercial brands of
Sitopaladi churna
were standardized based on powder microscopy, physico-chemical evaluations, thin layer chromatography (TLC) and high performance thin layer chromatography (HPTLC) finger printing as per standard procedures.
Results:
The set parameters were sufficient to evaluate the churna based on various physico-chemical parameters.
Conclusion:
The data evolved can be adopted for laying down the standards for the manufacturing units of
Sitopaladi churna
.
[ABSTRACT]
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5,858
361
2
LETTER TO EDITOR
Challenge of infertility: How protective the yoga therapy is?
Pallav Sengupta
July-September 2012, 32(1):61-62
DOI
:10.4103/0257-7941.113796
PMID
:23929997
[FULL TEXT]
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[PubMed]
5,813
297
5
ORIGINAL ARTICLES
Evaluation of antidiabetic, antioxidant effect and safety profile of gomutra ark in Wistar albino rats
Devender O Sachdev, Devesh D Gosavi, Kartik J Salwe
January-March 2012, 31(3):84-89
DOI
:10.4103/0257-7941.103180
PMID
:23284212
The effect of Gomutra ark (GoA) on experimental alloxan-induced diabetes in rats was studied. For this purpose, Wistar albino rats of either sex weighing 200-250 g were used. The biochemical parameters like blood sugar, vitamin C, and malondialdehyde release were measured. The safety profile of GoA was evaluated using acute and chronic toxicity studies. GoA significantly lowers blood glucose in diabetic rats although the observed effect was found to be less than glibenclamide. It significantly lowers the level of malondialdehyde and vitamin C in diabetic rats. No toxicity was observed even when cow urine was given 32 times of the study dose in acute toxicity and no significant changes were seen when it was used chronically, which suggests that cow urine is having a very high therapeutic index. This study supports the traditional use of GoA in diabetes and is having a high therapeutic index and is safe for chronic use. However, further studies are needed to elucidate the mechanism of action of Gomutra ark.
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5,464
601
2
BOOK REVIEW
Angamardhana: A treatise on massage techniques of ancient India
BS Praveen
January-March 2017, 36(3):170-171
DOI
:10.4103/asl.ASL_162_16
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5,591
364
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ORIGINAL ARTICLES
Validation of standard manufacturing procedure of
Guḍūcī sattva
(aqueous extract of
Tinospora cordifolia
(Willd.) Miers) and its tablets
Rohit Sharma, Hetal Amin, Galib , PK Prajapati
July-September 2013, 33(1):27-34
DOI
:10.4103/0257-7941.134564
PMID
:25161327
Introduction:
Guḍūci
Sattva
is a highly valued formulation among ayurvedic physicians, commonly recommended in conditions such as
Jvara
(fever),
Dāha
(burning sensation) and other conditions of
Pitta
predominance. In spite of its numerous medicinal attributes, no published work is available until date on manufacturing guidelines along with its quality control parameters.
Aims
and
Objectives:
The aim of this study is to develop the standard manufacturing procedure for preparation of
Guḍūci
Sattva
and its tablets.
Materials
and
Methods:
A total of 15 batches of
Guḍūci
Sattva
were prepared in the laboratory. During its preparation, pharmaceutical findings and observations were systematically recorded. To maintain quality control,
Guḍūci
Sattva
tablets were further subjected to analysis such as shape, diameter, width, hardness, weight variation, disintegration time (DT) and friability. Qualitative analysis to detect the presence of various functional groups and high performance thin layer chromatography (HPTLC) profile were also carried out.
Results
and
Conclusion:
The average percentage of dried
Sattva
obtained was 3.8%. The tablets were prepared by direct compression method as per pharmacopoeal specifications. Optimum hardness, weight of tablets, DT and friability of
Guḍūci
Sattva
tablets were found complying with official standards. Alkaloids, carbohydrates and starch were found present in
Sattva
tablets. Number of peaks obtained in HPTLC also corresponds to this finding. Data obtained by present study may be considered as standard for future studies.
[ABSTRACT]
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[PubMed]
4,934
981
1
REVIEW ARTICLE
Significance of gingers (Zingiberaceae) in Indian System of Medicine - Ayurveda: An overview
Konickal Mambetta Prabhu Kumar, Gopinathan Ramanikutty Asish, Mamiyil Sabu, Indira Balachandran
April-June 2013, 32(4):253-261
DOI
:10.4103/0257-7941.131989
PMID
:24991077
Background:
Family Zingiberaceae consists of the large number of medicinal plants and is well-known for its use in ethnomedicine and play a major role in Indian System of Medicine, Ayurveda.
Objective:
The aim of this study is the documentation of Zingiberaceous plants used in Ayurveda, adding information to the systematics, vernacular names and chemistry with experimental data.
Materials and Methods:
The live plants were collected from wild and successfully conserved at Herbal Garden of Arya Vaidya Sala, Kottakkal. The experimental data of each species has been collected from the various sources. The photographs were taken and all relevant data documented.
Results
and
Conclusion:
A total of 13 species belonging to 7 genera of Zingiberaceae were documented. The work will be useful to students and researchers as it provides an easy access to Zingiberaceous plants used in Ayurveda.
[ABSTRACT]
[FULL TEXT]
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[EPub]
[CITATIONS]
[PubMed]
5,435
288
14
BOOK REVIEW
Textbook of "Knowledge Traditions and Practices of India"
Kapil Kapoor, Michel Danino
July-September 2012, 32(1):59-60
[FULL TEXT]
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[EPub]
5,203
493
-
ORAL PRESENTATIONS
OA01.09. Management of systolic hypertension with shirodhara
Pankaj P Tathed, Nitin M Kamat
October-December 2012, 32(5):9-9
Purpose:
Increase in the lateral pressure exerted by the flowing blood during the contraction of the heart is termed as SYSTOLIC HYPERTENSION, which causes adverse effects on many organs including vital organs and leads to multi-organ failure. Many medications acting at different levels are available in the conventional medicine, which are far from satisfactory and hence there is a need to find out cost effective and satisfactory alternatives.
Method:
30 newly diagnosed middle aged (30 to 50 years) patients of either sex with a range of 140 to 160 systolic blood pressure (Diastolic B.P < 90 mm.of Hg) were recruited for Tila Taila (Oil of Saeasum Indicum Linn) Shirodhara 30 minutes daily for 14 days. Blood pressure was monitored in the morning, before and after Shirodhara, in evening and the record was analysed.
Result:
It was observed that on 1st day Systolic B.P reduced by 4 to 8 mm.of Hg at the end of Shirodhara, but remained the same as initial blood pressure by the evening. At the end of the 7th day B.P reduced by 8 to 12 mm of Hg after Shirodhara and B.P was low by 6 to 10 mm of Hg in the morning and evening. Similar results were observed on 14th day. A striking observation was made that those patients having heaviness in the chest did not complain of the symptom after first week of Shirodhara. Feeling of well being and sound sleep was also reported after starting the treatment.
Conclusion:
Hence, it can be concluded that non-invasive modality like Shirodhara which is devoid of any unwanted effects can be used for control of systolic hypertension.
[ABSTRACT]
Full text not available
[PDF]
5,549
120
-
REVIEW ARTICLE
Śodhana: An Ayurvedic process for detoxification and modification of therapeutic activities of poisonous medicinal plants
Santosh Kumar Maurya, Ankit Seth, Damiki Laloo, Narendra Kumar Singh, Dev Nath Singh Gautam, Anil Kumar Singh
April-June 2015, 34(4):188-197
DOI
:10.4103/0257-7941.160862
PMID
:26283803
Ayurveda involves the use of drugs obtained from plants, animals, and mineral origin. All the three sources of drugs can be divided under poisonous and nonpoisonous category. There are various crude drugs, which generally possess unwanted impurities and toxic substances, which can lead to harmful health problems. Many authors have reported that not all medicinal plants are safe to use since they can bear many toxic and harmful phytoconstituents in them.
Śodhana
(detoxification/purification) is the process, which involves the conversion of any poisonous drug into beneficial, nonpoisonous/nontoxic ones.
Vatsanābha
(
Aconitum
species),
Semecarpus anacardium, Strychnos nux-vomica, Acorus calamus, Abrus precatorius
etc., are some of the interesting examples of toxic plants, which are still used in the Indian system of medicine.
Aconite
, bhilawanols, strychnine, β-asarone, abrin are some of the toxic components present in these plants and are relatively toxic in nature.
Śodhana
process involves the purification as well as reduction in the levels of toxic principles which sometimes results in an enhanced therapeutic efficacy. The present review is designed to extensively discuss and understand the scientific basis of the alternative use of toxic plants as a medicine after their purification process.
[ABSTRACT]
[FULL TEXT]
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[EPub]
[CITATIONS]
[PubMed]
5,199
389
8
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Online since 25 September, 2011