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  Indian J Med Microbiol
 

Figure 1: Effects of long-term administration of Calendula officinalis extract on the passive avoidance learning test. The effect of long-term oral administration of extract on the step-through latency (STLa) in the first acquisition trial (a), the number of trials to acquisition (b), STLr in the retention test after 24 (c) and 48 h (e), the time spent in the dark compartment during the retention test after 24 (d) and 48 h (f) between differ­ent control, diabetic, control + calendula and diabetic + calendula groups (n = 8). *P < 0.05, **P < 0.01 and ***P < 0.001 significant differences compared to control group. #P < 0.05, ##P < 0.01 and ###P < 0.001 significant differences compared to diabetic group. $P < 0.05, $$P < 0.01 and $$$P < 0.001 significant differences compared to diabetic + calendula group

Figure 1: Effects of long-term administration of <i>Calendula officinalis</i> extract on the passive avoidance learning test. The effect of long-term oral administration of extract on the step-through latency (STLa) in the first acquisition trial (a), the number of trials to acquisition (b), STLr in the retention test after 24 (c) and 48 h (e), the time spent in the dark compartment during the retention test after 24 (d) and 48 h (f) between differ­ent control, diabetic, control + calendula and diabetic + calendula groups (<i>n</i> = 8). *<i>P</i> < 0.05, **<i>P</i> < 0.01 and ***<i>P</i> < 0.001 significant differences compared to control group. #<i>P</i> < 0.05, ##<i>P</i> < 0.01 and ###<i>P</i> < 0.001 significant differences compared to diabetic group. $<i>P</i> < 0.05, $$<i>P</i> < 0.01 and $$$<i>P</i> < 0.001 significant differences compared to diabetic + calendula group